I cut out my FT Spitfire by hand, so yes, I have successfully cut out a plan by hand. I printed out the tiled plans of it and glued them to a sheet of poster board, like Josh suggests in this video:
I cut the outline out before cutting the foam board. (I've heard of people cutting the templates at the same time as the foam board after taping the plan onto the sheet of foam board.) I ended up using a small nail to punch holes through the plan and the foam board at the corners of places you were supposed to cut out, to mark the right point on the foam board, and then connected them by drawing a line using a ruler. I did this for the cutouts to fit the spar tabs on the lower surface of the wing.
In terms of what knives/blades I used, I just found a 100-pack of razor blades like what FliteTest uses in their build videos, and for the small cutouts and other tight curves and corners, I used a small xacto knife with a #11 blade.
(Sorry if this is too much detail and not enough visual aids/links. I'm happy to go find the things I used on Amazon and link them if that's useful.)
Hope this helps!