ezbruh
An interesting design but I fear you are seriously misjudging the power required to reach 100mph let alone any faster.
You estimated the weight as 1.2lbs. I expect you will need a thrust to weight of at least 1:1 and you certainly won't get that from a 40mm EDF.
An EDF accelerates the air and it does so across the width of the blade. Accelerating the air generates the thrust so It follows as much undisturbed air as possible must reach the fan. The whole air intake duct should have the same area as the rotating part of the Fan, its Swept Area.
Part of the losses in any duct are due to skin friction at the inner surface creating a slow moving boundary layer. Unfortunately the boundary lay thickness is constant so small size ducts have proportionally bigger losses than big ones. The boundary layer also suggests the duct should be circular to give the maximum cross section area for the minimum surface area. Unfortunately your narrow "crescent" inlet has a lot of surface for the area provided.
Of course both the airframe's frontal area and its surface area create drag which the EDF has to over come. Everything has to be both as small and streamlined as possible.
The difficult part is how you package the fixed bits like the battery, servos and radio needed to both power and control the plane but only adding the minimum frontal and surface area. It is not easy or simple.
You best bet would be to research what are the attributes of a know "fast" EDF, what power it uses and work from there.
I could be all wrong but from my own experience I don't think so.