I agree that it depends on what type of flying you see yourself doing. I do mostly 3S with limited acrobatics, never carry a go-pro since no one wants to watch my unskilled flying anyway.
With that in mind, I find glass-filled-nylon frames to suit my need. The weight is similar to most carbon fibre frames (or perhaps lighter than the heavy duty ones), it's slightly flexible such that it can take a good hit, but definitely stiff enough in the context of a 250 quad. And they are cheap, the whole frame with PDB often cost less than an arm of the branded carbon fibre frames.
The other consideration is how easy it is to mount equipment onto it (PDB, flight controller, camera, vtx, receiver, battery). This means that larger frames are generally better.
As I got better with building, I found myself moving towards smaller frames, they require more planning in the layout but are more manouevrable.