I'm pretty sure the tips are resonating like a reed in a tuba.
As a relapsed brass player myself I have to take offense at this. Reeds are for woodwinds!
As for what causes desyncs...it's a mix of hardware and software. Some versions of SimonK an newer versions of blheli are better than others. But the better hardware on the KISS makes it easier for them to avoid desyncs. Bigger and pitchier props also makes it more likely to happen.
What it comes down to is that what ESC's are doing is pretty mind boggling when it comes right down to it. Well, actually it's simple - just just have to turn 3 switches on and off. That's it. The FET's are those switches. That's why you have three wires coming off your motors. A brushless DC outrunner works by turning windings on the stator on and off to attract/repel the magnets on the bell. The faster the motor goes the faster those have to be turned on and off. If the ESC looses track of which is supposed to be on and which off and does so at the wrong time you end up with a desync and instead of pushing the bell around the motor momentarially tries to turn it the opposite way.
This is why KISS ESC's are so much quieter and why people are seeing longer flights with them. Having faster FET's that are able to switch on and off faster along with better software that keeps them from loosing sync the motors run better because they're not fighting themselves when the timing gets off. How much does the timing have to be off? Well, let's see...2400kv motor at 12v would be almost 29k RPM or 480 revolutions per second. So every second that bell is going aruond 480 times. To get around once the coils have to be switched several times - it varies with the wind of the motor and polecount but we'll go with 6 for the sake of argument. So that's about 2,800 times a second things need to be switched. That's why I say it's pretty mind boggling despite being pretty simple
Even if my math is off on the exact numbers the point is those FET's are switching on and off thousands of times a second with these high kv motors. They still switch pretty freaking fast even on lower Kv motors, but on high Kv motors things get mind numbing fast. That's why desync's weren't a common problem until the rise of the mini's.