I'd imagine it'd be difficult since the movements are much slower and more precise. Probably almost doable on something like a slow flying glider.
LOL actually, you need MORE throw on a slow flying glider than on a fast aircraft like a hotliner. That's why guys set up different rates for things like 3D flight and IMAC flight - that way, if you're flying fast and trying to do a more precision maneuver, you can throw it into a specific rate with lower throws, but if you're trying to do high alpha slow flight, you may need that high throw capability to give more control.
All this said, I myself wouldn't do it in real life. Too much of a chance to crash, or worse, injure someone...Give it a shot on a sim first; you'll see how it can go wrong fairly quickly, and there's no chance of injuring someone or having to repair your plane if you can't keep it under control.