Depends what it is. Technically you can fly a 3ch plane with 3 channels but a dedicated helicopter TX may have some special mixing that won't work with planes.
Same goes for RC flight simulators. Also, generally flight simulators require PPM out usually from a trainer port for the TX to work.
So post the brand and model and maybe we can be more definitive.
However, if you want to get started you should probably consider buying something a bit more capable. There are various ways to go but if you want to build FliteTest planes getting a computer radio that does servo reverse, endpoints and subtrim is very useful. A few extra channels and mixes adds to the fun. You can start with something more basic if you want but if you are interested you will learn fast.
The cheapest programmable TX, around $30 US that has useful features is the
HobbyKing T6A/FlySky CT6B. You need a computer to program it and don't for get to
buy the USB programming cable
The next is the
FlySky i6 with the iA6B receiver for around $50 US. You don't need a computer to use it and it has much better features.
In both cases you may need some additional cables to hook up to a flight simulator. I can find links to those if you are interested.
These are cheap radios so quality is not always there but they have all the essential features to get started.
There are other more expensive choices that have better quality and support.